[Esophageal atresia: a second-level hospital experience]
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Updated: Aug 14, 2026

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Published on: September 22, 2023
Carlos Baeza-Herrera1, Javier López-Castellanos, José Luis Atzin-Fuentes
1Academia Mexicana de Cirugía, UNAM, Hospital Pediátrico Moctezuma.
Insights
Surgical outcomes for esophageal atresia with tracheoesophageal fistula are improving, but high-risk newborns with specific factors still face significant mortality. Identifying these risk factors is crucial for improving survival rates in esophageal atresia cases.
Area of Science:
- Pediatric Surgery
- Neonatology
- Congenital Malformations
Context:
- Surgical correction of esophageal atresia with distal tracheoesophageal fistula has advanced.
- A subset of high-risk newborns continues to experience considerable mortality.
- Associated factors like low birth weight, prematurity, and respiratory distress impact outcomes.
Purpose:
- To analyze mortality rates in newborn infants undergoing treatment for esophageal atresia variants.
- To identify specific risk factors influencing mortality in this patient population.
- To evaluate the impact of associated malformations and gestational age on survival.
Summary:
- This retrospective study analyzed 80 infants with esophageal atresia variants treated between 1999 and 2003.
- Mortality was observed in 41 infants, with logistic regression identifying significant risk factors.
- Identified variables demonstrated relevant statistical significance in influencing patient outcomes.
Impact:
- Highlights critical risk factors associated with higher morbidity and mortality in esophageal atresia.
- Informs clinical decision-making for high-risk newborns with tracheoesophageal fistula.
- Emphasizes the need for targeted interventions to improve survival rates in complex esophageal atresia cases.
Introduction:
In recent years, surgical correction of esophageal atresia with distal tracheoesophageal fistula has become increasingly successful. However, there is still a group of high-risk patients with specific factors in whom the mortality remains appreciable. These associated factors include weight, gestational age, associated malformations and respiratory distress.
Material And Methods:
This report analyzes the mortality in 80 newborn infants with variants of esophageal atresia with or without tracheoesophageal fistula who were treated from 1999 to 2003. Data were collected restrospectively from hospital and office records.
Results:
We observed 42 male patients, 69 patients were C variety, all had more than 12 h of postnatal life, 34 were preterm newborn, 41 were classified A or B according to Waterston, and 41 died. A logistic regression analysis and chi2 of the influence of each risk factor on mortality was performed. Relevant statistical significance was found in the studied variables.
Conclusions:
Morbidity and mortality of esophageal atresia was higher due to identified risk factors.
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