Related Experiment Video
Updated: Aug 14, 2026

Characterization of Sickling During Controlled Automated Deoxygenation with Oxygen Gradient Ektacytometry
Published on: November 5, 2019
Sickle cell disease: a stigmatizing condition that may lead to depression
Coretta Jenerette1, Marjorie Funk, Carolyn Murdaugh
1Yale University, School of Nursing, New Haven, CT 06536, USA. cmj26@email.med.yale.edu
Abstract:
Individuals with a chronic illness such as sickle cell disease are at risk for depression. Moreover, they are at risk for untreated depression. Depression may go untreated because of the stigma and high rates of disability associated with this chronic illness that most often affects African Americans in the United States. The purpose of this cross-sectional study was to describe depressive symptoms using the Beck Depression Inventory Fast Screen in a sample of 232 African American adults with sickle cell disease. Respondents reported higher levels of depression (26%) and depressive symptoms (32%) than did the overall United States population (9.5%). All adults with chronic illnesses need to be screened for depression in primary care practice sites where the diagnosis and treatment of depression needs to be coordinated.
Related Concept Videos
Depressive Disorders: Etiology
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Stress and Mental Health
Individuals with depression often experience challenges in both their personal and professional...
Depression: Overview
Depressive Disorders: MDD and Dysthymia
Stress Prevention and Stress Management Techniques IV
Psychoneuroimmunology: Diabetes and Cancer
