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Related Concept Videos

Allergic Reactions02:06

Allergic Reactions

Overview
Asthma-I: Introduction01:29

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
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Drug-related allergies are immune-mediated responses triggered by the administration of pharmacological agents. These hypersensitivity reactions are classified based on the immune mechanisms involved. The four primary types—Type I, II, III, and IV—are mediated by different immunological pathways and exhibit distinct clinical manifestations.Type I Hypersensitivity/ IgE-Mediated Reactions: Immunoglobulin E (IgE) immediately mediates Type I hypersensitivity reactions. Upon initial exposure to a...
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Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...
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Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
Asthma III: Clinical Manifestations01:13

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Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...

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[Occupational allergy to mugwort].

Marina Kurzen1, Christiane Bayerl, Sergij Goerdt

  • 1Klinik für Dermatologie, Venerologie und Allergologie am Klinikum Mannheim gGmbH, Universitätsklinikum der Ruprecht-Karls-Universität Heidelberg. Marina.Kurzen@haut.ma.uni-heidelberg.de

Journal Der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG
|November 16, 2005
PubMed
Summary
This summary is machine-generated.

A florist experienced a severe allergic reaction to mugwort (Artemisia vulgaris), highlighting its potent allergenicity. This case underscores the occupational risks associated with mugwort exposure, even in individuals without oral allergy syndrome.

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Area of Science:

  • Allergology
  • Occupational Health

Background:

  • Mugwort (Artemisia vulgaris) is traditionally used in cuisine and medicine.
  • Mugwort pollen is a known trigger for pollinosis, with cross-reactivity to Umbelliferae family members.
  • The Artemisia genus includes species like Artemisia absinthum and Artemisia dracunculus (estragon).

Observation:

  • A florist with a sunflower allergy developed life-threatening glottal edema after occupational mugwort contact.
  • The patient did not exhibit oral allergy syndrome to mugwort pollen cross-reactants.

Findings:

  • Skin testing showed strong sensitization to mugwort and estragon.
  • Elevated specific IgE antibodies were detected for mugwort, sunflower, carrots, celery, fennel, and anis.

Implications:

  • This case highlights the significant allergenic potential of Artemisia vulgaris.
  • It documents the occupational significance of mugwort allergy for the first time.
  • Severe mugwort allergy can lead to life-threatening complications.