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Updated: Aug 14, 2026

A Mouse Distraction Osteogenesis Model
Published on: November 14, 2018
[Design and application of internal devices for automatic elasticity distraction osteogenesis]
Hong-zhi Zhou1, Min Hu, Kai-jin Hu
1Dept. of Oral and Maxillofacial Surgery, College of Stomatology, Fourth Military Medical University, Xi'an 710032, China.
Objective:
To improve the design of the devices used for autoatic elasticity distraction osteogenesis, and to preliminarily testify their feasibility for clinical application.
Methods:
The internal automatic distraction devices were constructed by three parts, including sinusoid shape memory alloy distractor, reconstructive plate and mini-plate. The animal model of trifocal bone transport reconstruction of canine mandibular mentis was duplicated, in which a 6 cm mandibular mentis segment was removed and the transport disc was created by osteotomy in both ends of the mandibular defect. The plates were used for internal fixation and shape reconstruction of the mandible. They also served as transport distraction guidance for the elasticity distractor.
Results:
The new devices could complete bone transport as expected. Regenerated bone segments were formed in two months and both sides of the mandibular body were lengthened. Because of the narrow angle and obstruction from the thick soft tissues in the mentis area, the ultimate symphysis mentalis was not reconstructed.
Conclusion:
The design of the internal elasticity distraction devices showed potential feasibility for clinical practice. But further studies are still needed for better control of the strength and balance of distraction forces.
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