Related Experiment Video
Updated: Aug 4, 2026

Implementation of In Vitro Drug Resistance Assays: Maximizing the Potential for Uncovering Clinically Relevant Resistance Mechanisms
Published on: December 9, 2015
Molecular signatures of natural selection
1Center for Bioinformatics and Department of Evolutionary Biology, University of Copenhagen, 2100 Copenhagen Ø, Denmark. rasmus@binf.ku.dk
Abstract:
There is an increasing interest in detecting genes, or genomic regions, that have been targeted by natural selection. The interest stems from a basic desire to learn more about evolutionary processes in humans and other organisms, and from the realization that inferences regarding selection may provide important functional information. This review provides a nonmathematical description of the issues involved in detecting selection from DNA sequences and SNP data and is intended for readers who are not familiar with population genetic theory. Particular attention is placed on issues relating to the analysis of large-scale genomic data sets.
Related Concept Videos
What is Natural Selection?
Limits to Natural Selection
Gene Evolution - Fast or Slow?
In contrast, regions which code...
Gene Evolution - Fast or Slow?
In contrast, regions which code...
Natural Selection and Adaptation
Beyond physical adaptations, psychological...
Natural Selection and Mating Preferences
Females, due to their biological roles in conception, pregnancy, and nursing, inherently...

