Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Liver regeneration after split liver transplantation.

Hui-Xing Chen1, Guang-Wen Zhou, Lu Yin

  • 1Center of Organ Transplantation, Ruijin Hospital, Shanghai Second Medical University, Shanghai 200025, China. huixingchen@hotmail.com

Hepatobiliary & Pancreatic Diseases International : HBPD INT
|November 16, 2005
PubMed
Summary

Split liver transplantation (SLT) grafts show significant regeneration, adapting to recipient needs over time. Functional recovery often precedes full size restoration, ensuring metabolic demands are met post-transplant.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Role of Ferroptosis in Paraquat-Induced Acute Lung Injury in Mice].

Fa yi xue za zhi·2026
Same author

Integrating multiphase MRI surrogates to improve microvascular invasion detection and recurrence risk stratification in HCC.

JHEP reports : innovation in hepatology·2026
Same author

[Distribution， Source Analysis， and Risk Assessment of Typical Emerging Contaminants in Groundwater Around Industrial Enterprises in South China].

Huan jing ke xue= Huanjing kexue·2026
Same author

Effect of frequency side channels on the security of practical quantum key distribution.

Optics express·2025
Same author

Mendelian randomization analysis does not reveal a causal influence of smoking on rotator cuff tears.

Medicine·2025
Same author

Analysis of Modification Zones in Mandibular Complete Denture Models Designed with the Bio-Functional Prosthetic System.

Therapeutics and clinical risk management·2025

Area of Science:

  • Hepatology
  • Transplantation Surgery
  • Regenerative Medicine

Background:

  • Split liver transplantation (SLT) is increasingly utilized.
  • Investigating graft liver regeneration post-SLT is crucial due to potential size discrepancies.
  • Understanding graft adaptation is key for successful outcomes.

Observation:

  • Four SLT cases were analyzed, monitoring graft liver volume (GLV) and biochemical markers.
  • Computed tomography (CT) measured GLV against recipient standard liver volume (SLV).
  • Liver volume regeneration ratio (LVRR) and serum levels (AST, ALT, TB, PA, ALB) were tracked postoperatively.

Findings:

  • Graft liver volume generally converged towards the recipient's standard liver volume over 360 days.
  • Liver volume regeneration ratio (LVRR) indicated adaptive growth in most cases.

Related Experiment Videos

  • Biochemical markers normalized, with functional recovery (ALT, AST, TB) preceding complete morphological restoration.

    • Implications:

    • SLT grafts demonstrate adequate regeneration to meet metabolic demands.
    • Functional graft recovery is an early indicator of successful transplantation.
    • This regeneration capacity supports the clinical viability of SLT.