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Cell-based cardiac repair: reflections at the 10-year point

Charles E Murry1, Loren J Field, Philippe Menasché

  • 1Center for Cardiovascular Biology and Regenerative Medicine, University of Washington, Seattle, WA 98195, USA. murry@u.washington.edu

Circulation
|November 16, 2005
PubMed
Summary

No abstract available in PubMed .

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After cellular or tissue damage, the resident stem cells present in the human body can locally repair and regenerate the damaged tissue or organ. However, even though some tissues do not have stem cells, they can repair and regenerate with the help of pre-existing cells. For example, beta cells of the pancreas and hepatocytes of the liver can divide to renew and regenerate the tissue. Here, both cell division and cell death are well regulated by homeostasis.
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