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The association between nuchal nevus flammeus and alopecia areata: a case-control study
Maryam Akhyani1, Farshad Farnaghi, Hassan Seirafi
1Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Background:
The association of alopecia areata (AA) with nuchal nevus flammeus (NNF) has been demonstrated by previous studies.
Objectives:
The aim of this study was to investigate whether AA is associated with NNF.
Methods:
199 AA patients and 215 controls without AA were examined for the presence of NNF.
Results:
35 patients (17.6%) in the AA group had NNF. In the control group, 20 patients (9.3%) had NNF (odds ratio = 2.08, 95% confidence interval 1.43-2.73; p = 0.013). A statistically significant association was found between the presence of NNF and duration of the AA (p < 0.001). The presence of NNF was associated with severity of AA (p < 0.001).
Conclusions:
The results of our study suggest a link between NNF and AA especially in severer and more chronic forms.
