Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Is running performance enhanced with creatine serum ingestion?

Todd A Astorino1, Andrew C Marrocco, Sara M Gross

  • 1Department of Kinesiology, California State University, San Marcos, California 92096, USA. astorino@csusm.edu

Journal of Strength and Conditioning Research
|November 17, 2005
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same authorSame Topic

Acute hemodynamic responses to high intensity interval training, moderate intensity continuous training, and vigorous intensity continuous training in active men.

Frontiers in physiology·2026
Same author

Impact of High-Intensity Interval Training on Cardiometabolic Risk Factors in Youth With Overweight/Obesity: A Systematic Review and Meta-Analysis.

Pediatric exercise science·2026
Same author

Cardiometabolic response to high intensity functional training versus rowing-based high intensity interval training.

Sports medicine and health science·2026
Same author

The effect of low volume sprint interval training on cardiorespiratory fitness: study protocol for a definitive randomized controlled trial.

Trials·2026
Same author

Lessons from history for <math><mrow><mover><mi>V</mi> <mo>˙</mo></mover> <msub><mi>O</mi> <mn>2</mn></msub></mrow></math> max and the <math><mrow><mover><mi>V</mi> <mo>˙</mo></mover> <msub><mi>O</mi> <mn>2</mn></msub></mrow></math> plateau, part 1, 1920 - 1961: original concepts were based on discontinuous exercise protocols.

Frontiers in physiology·2025
Same author

No sex differences in fat oxidation in response to exercise prescribed according to maximal heart rate or ventilatory threshold.

European journal of applied physiology·2025

Runners Advantage creatine serum did not significantly improve 5,000-m run times or VO2max in runners. While some measures like perceived exertion decreased, the overall ergogenic claims are not supported by this study.

Area of Science:

  • Sports Science
  • Exercise Physiology
  • Nutritional Supplementation

Background:

  • Creatine supplementation is popular for enhancing athletic performance.
  • Runners Advantage (RA) creatine serum is marketed to improve running capacity.
  • Scientific validation of RA's ergogenic effects is needed.

Purpose of the Study:

  • To investigate the efficacy of Runners Advantage (RA) creatine serum on running performance.
  • To assess the impact of RA on physiological markers during exercise.
  • To determine if RA provides a significant ergogenic benefit to cross-country runners.

Main Methods:

  • Cross-country runners underwent baseline testing including a 5,000-m run and VO2max assessment.
  • Subjects ingested either RA (2.5g creatine) or a placebo.

Related Experiment Videos

  • Physiological data (heart rate, RPE, VO2max, Vco2max) and performance metrics (run time) were recorded.
  • Main Results:

    • RA supplementation showed a statistically significant increase in VO2max compared to baseline, but the magnitude was within the test's variability.
    • Maximal heart rate was unaffected, but Vco2max and exercise duration increased with RA.
    • 5,000-m run time remained unchanged, and rating of perceived exertion (RPE) was lower with RA compared to baseline.

    Conclusions:

    • The current dose and form of Runners Advantage creatine serum do not provide significant ergogenic benefits for running performance.
    • Observed improvements in VO2max and exercise duration with RA were not substantial enough to support marketing claims.
    • Further research may be needed to explore optimal creatine delivery methods or dosages for runners.