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[Chronic relapsing axonal neuropathy. A case report].

J M Pardal-Fernández1, B Godes-Medrano, B Rallo-Gutiérrez

  • 1Unidad de Electromiografía Clínica, Servicio de Neurofisología, Hospital General Universitario de Albacete, 02006 Albacete, Spain. josempardal@yahoo.es

Revista De Neurologia
|November 17, 2005
PubMed
Summary
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This case study details a rare, chronic, recurring axonal polyneuropathy (PNP) in an adult male. The condition led to progressive disability over ten years, highlighting the need for its consideration in diagnosing similar nerve disorders.

Area of Science:

  • Neurology
  • Peripheral Nervous System Disorders

Background:

  • Polyneuropathies (PNP) arise from nerve damage and are classified by various characteristics.
  • This report focuses on a prolonged follow-up of an adult male with chronic, recurring axonal-type PNP.

Observation:

  • A 65-year-old male experienced neurological deficits over 10 years with relapsing-remitting episodes.
  • Progressive functional limitations and extreme disability were noted with each relapse.
  • Neurophysiological studies confirmed sensory and motor axonal injury without demyelination.

Findings:

  • Extensive investigations excluded specific causes for the polyneuropathy.
  • The clinical course and electrophysiological findings supported a diagnosis of chronic primary axonal PNP.
  • This represents a rare, likely underdiagnosed, condition.

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Implications:

  • This case adds to the limited literature on recurring axonal polyneuropathy.
  • It emphasizes the importance of considering this diagnosis in cases of chronic, relapsing PNP.
  • The condition often shows a poor response to therapy, impacting prognosis.