Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hypertriglyceridemia: apheretic treatment.

G Giannini1, M Valbonesi, F Morelli

  • 1Department of Immunohematology, Immunohematology Services, S. Martino University Hospital, Genova--Italy. gabriella.giannini@hsanmartino.it

The International Journal of Artificial Organs
|November 17, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The role of the molecular tumor board: learnings from the ROME trial.

NPJ precision oncology·2026
Same author

Safety and Efficacy of Portal Vein Recanalization with Creation of Intrahepatic Portosystemic Shunt (PVR-TIPS) to Treat Chronic Portal Vein Thrombosis in Non-cirrhotic Patients.

Cardiovascular and interventional radiology·2025
Same author

A novel multisensory device for the assessment and rehabilitation of perceptual and attentional competencies.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2023
Same author

Early visual deprivation disrupts the mental representation of numbers in visually impaired children.

Scientific reports·2022
Same author

Author Correction: Effects of climate variation on bird escape distances modulate community responses to global change.

Scientific reports·2021
Same author

Search for Displaced Leptons in sqrt[s]=13  TeV pp Collisions with the ATLAS Detector.

Physical review letters·2021
Same journal

Therapeutic plasma exchange added to CRRT combined with hemoperfusion in wasp sting-associated AKI: A multicenter retrospective cohort study.

The International journal of artificial organs·2026
Same journal

Development of an early prediction model for ICU-acquired weakness in sepsis using PNI and SII.

The International journal of artificial organs·2026
Same journal

Foot care behaviors and perceived exercise benefits and barriers in diabetic hemodialysis patients.

The International journal of artificial organs·2026
Same journal

First clinical experience with citrate-anticoagulated CVVHD-based low-flow ECCO<sub>2</sub>R in severe hypercapnic respiratory failure.

The International journal of artificial organs·2026
Same journal

Carboxyhemoglobin levels for the detection of hemolysis in patients supported by left ventricular assist devices: A case series.

The International journal of artificial organs·2026
Same journal

Evaluation of arteriovenous fistulas of obtuse anastomosis in reducing thrombosis using computational fluid dynamics.

The International journal of artificial organs·2026
See all related articles

Severe hypertriglyceridemia, a risk factor for pancreatitis, was treated using plasmapheresis or cascade filtration. Both methods showed moderate triglyceride removal rates in patients post-bone marrow transplant.

Area of Science:

  • Biochemistry
  • Nephrology
  • Transplantation

Background:

  • Extremely high triglyceride levels (hypertriglyceridemia) pose a significant risk for acute pancreatitis.
  • Hypertriglyceridemia results from increased production or impaired clearance of triglyceride-rich lipoproteins, often exacerbated by secondary causes.
  • Cyclosporin A, used post-bone marrow transplantation, can complicate patient care by affecting lipid metabolism.

Purpose of the Study:

  • To evaluate the efficacy of plasmapheresis and cascade filtration in managing severe hypertriglyceridemia.
  • To compare triglyceride removal rates between plasmapheresis and cascade filtration in patients receiving Cyclosporin A post-bone marrow transplant.

Main Methods:

  • A cohort of 15 patients with hypertriglyceridemia post-bone marrow transplantation were treated.

Related Experiment Videos

  • Five patients underwent plasmapheresis, while ten patients were treated with cascade filtration.
  • Triglyceride levels and removal rates were monitored for both treatment groups.

    • Main Results:

    • Plasmapheresis achieved a triglyceride removal rate of 63.5%.
    • Cascade filtration resulted in a triglyceride removal rate of 58.0%.
    • These removal rates were considered moderate, potentially due to filter saturation.

    Conclusions:

    • Both plasmapheresis and cascade filtration demonstrate efficacy in reducing triglyceride levels in severe hypertriglyceridemia.
    • Further investigation is needed to optimize extracorporeal therapies and mitigate filter saturation for improved triglyceride clearance.