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Updated: Aug 14, 2026

Helical Organization of Blood Coagulation Factor VIII on Lipid Nanotubes
Published on: June 3, 2014
Natively unfolded regions of the vertebrate fibrinogen molecule
Russell F Doolittle1, Justin M Kollman
1Division of Biological Sciences, Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California 92093-0634, USA. rdoolittle@ucsd.edu
Abstract:
Although it has long been realized that a large portion of the fibrinogen alpha chain has little if any defined structure, the physiological significance of this flexible appendage remains mysterious.
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