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Updated: Aug 14, 2026
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Biosensor for Detection of Antibiotic Resistant Staphylococcus Bacteria
Published on: May 8, 2013
Clindamycin-resistance in methicillin-resistant Staphylococcus aureus isolated from animals
M Rich1, L Deighton, L Roberts
1Microbiology Department, IDEXX Laboratories, Sandbeck Way, Wetherby, West Yorkshire LS22 7DN, UK. mick-rich@idexx.com
Veterinary Microbiology
|November 18, 2005
Summary
A simple D-test detected inducible clindamycin resistance in 71% of animal MRSA isolates. This hidden resistance, missed by standard tests, is crucial for effective veterinary treatment.
Area of Science:
- Veterinary Microbiology
- Antimicrobial Resistance
Background:
- Clindamycin is a key antibiotic in veterinary medicine.
- Staphylococcal resistance can stem from target site modification via erm genes.
- Inducible resistance is often undetected by standard susceptibility tests.
Purpose of the Study:
- To evaluate the prevalence of inducible clindamycin resistance in animal MRSA isolates.
- To assess the utility of the D-test for detecting this resistance mechanism.
Main Methods:
- The double disc agar diffusion test (D-test) was employed.
- Two hundred and eighty-five methicillin-resistant Staphylococcus aureus (MRSA) isolates from animal infections were analyzed.
Main Results:
- 71% (107/285) of MRSA isolates exhibited inducible clindamycin resistance.
- This resistance was not apparent through initial routine susceptibility testing.
Conclusions:
- Inducible clindamycin resistance is highly prevalent in animal MRSA.
- Routine D-testing is recommended to identify inducible resistance, preventing treatment failures.
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