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Related Experiment Videos

Response of Charité total disc replacement under physiologic loads: prosthesis component motion patterns.

Patrick O'Leary1, Michael Nicolakis, Mark A Lorenz

  • 1Musculoskeletal Biomechanics Laboratory, Department of Veterans Affairs, Edward Hines Jr. VA Hospital, 5th Ave. and Roosevelt Rd., Hines, IL 60141, USA.

The Spine Journal : Official Journal of the North American Spine Society
|November 18, 2005
PubMed
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Total disc replacement (TDR) restores motion but alters spinal biomechanics under load. Charité TDR shows varied component motion and load-displacement patterns, necessitating further study on wear and load sharing.

Area of Science:

  • Spine biomechanics
  • Orthopedic implant technology
  • Biomedical engineering

Background:

  • Total disc replacement (TDR) aims to alleviate discogenic pain and preserve spinal motion.
  • The Charité TDR's floating core design theoretically mimics healthy disc kinematics under load.
  • Limited data exists on TDR's response to physiologic compressive preload and component motion.

Purpose of the Study:

  • To evaluate if Charité TDR restores normal lumbar motion segment load-displacement behavior under physiologic loads.
  • To investigate the relative motion of Charité TDR components within the lumbar spine.

Main Methods:

  • Biomechanical analysis of five human lumbar spine specimens (L1-sacrum).
  • Testing under flexion and extension moments with 0 N and 400 N compressive preloads.

Related Experiment Videos

  • Optoelectronic measurement of segmental motion and video-fluoroscopy assessment of prosthesis component kinematics.

    • Main Results:

    • Charité TDR significantly increased lumbar segment range of motion and segmental lordosis.
    • Four distinct patterns of prosthesis component motion were observed, including angular motion, lift-off, core entrapment, and translation.
    • Physiologic preload altered load-displacement curves, showing regions of both reduced and increased angular change compared to intact segments.

    Conclusions:

    • Charité TDR restores near-normal motion quantity but alters motion quality under preload.
    • Predominant motion occurred between the upper end plate and core, with varied component interactions observed.
    • Implant factors and preload magnitude influence TDR function; further research on wear and load sharing is required.