Congenital heart defect with associated malformations in children

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Michał Wojtalik1, Wojciech Mrówczyński, Jacek Henschke

  • 1Department of Paediatric Cardiac Surgery, Karol Marcinkowski University of Medical Sciences, Poznan 60-572, Poland.

Journal of Pediatric Surgery
|November 18, 2005
PubMed

Insights

Congenital heart defects (CHD) with other system malformations in children increase mortality risk. Younger age, urgent procedures, and primary cardiac surgery negatively impact outcomes, though some interventions can stabilize patients.

Area of Science:

  • Pediatric Cardiology
  • Congenital Malformations
  • Surgical Outcomes

Background:

  • Multisystem involvement in children, including congenital heart defects (CHD), presents significant clinical challenges.
  • Evaluating the incidence and treatment of CHD with associated malformations is crucial for pediatric cardiac surgery patients.

Purpose of the Study:

  • To determine the incidence of CHD associated with malformations in other organ systems.
  • To assess treatment modalities and perioperative mortality in pediatric patients with complex CHD.

Main Methods:

  • Retrospective review of 1856 children's medical records from 1997 to 2002.
  • Investigation of connections between CHD and other lesions, with univariate and multivariate analyses.
  • Scrutiny of patient and perioperative variables influencing mortality risk.

Main Results:

  • 4.53% of children had CHD with associated malformations, most commonly affecting digestive, urinary, and nervous systems.
  • No direct relation was found between CHD and concomitant lesions.
  • Mortality (approx. 19%) was significantly influenced by patient age, primary cardiac procedure, and CHD type.

Conclusions:

  • Treatment for children with CHD and multiple associated lesions carries a higher mortality risk.
  • Younger age, urgent procedures, and primary surgical interventions negatively impact patient outcomes.
  • Preceding cardiac procedures can improve outcomes through circulatory stabilization if the patient's condition permits.
Abstract

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