Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Stable ensemble performance with single-neuron variability during reaching movements in primates.

Jose M Carmena1, Mikhail A Lebedev, Craig S Henriquez

  • 1Department of Neurobiology, Center for Neuroengineering, Duke University, Durham, North Carolina 27710, USA.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
|November 18, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Editorial: Exoskeleton gait training.

Frontiers in neuroscience·2025
Same author

Spinal cord stimulation restores locomotion in a Parkinson's disease patient and rodents.

Brain stimulation·2025
Same author

Editorial: Datasets for brain-computer interface applications, volume II.

Frontiers in neuroscience·2025
Same author

Features of the interaction of 5-[4'-(6″-aminopurin-2″-yl)phenyl]-10,15,20-tri(N-methylpyridin-3'-yl)-porphyrin with nucleic acids.

International journal of biological macromolecules·2025
Same author

Olfactory neurofeedback: current state and possibilities for further development.

Frontiers in human neuroscience·2024
Same author

Restoration of natural somatic sensations to the amputees: finding the right combination of neurostimulation methods.

Frontiers in neuroscience·2024

Individual neuron activity varies during arm movements, but stable movement predictions are possible using neuronal ensembles. This supports redundant encoding in the motor cortex and informs brain-machine interface design.

Area of Science:

  • Neuroscience
  • Motor Control
  • Computational Neuroscience

Background:

  • Individual neuron firing properties exhibit significant variability during motor tasks.
  • The relationship between single neuron activity and movement parameters can be nonstationary.

Purpose of the Study:

  • To investigate the stability of arm movement prediction from neuronal activity.
  • To explore the concept of redundant encoding in the motor cortex.

Main Methods:

  • Recording neuronal activity from frontal and parietal cortical areas in two monkeys during a continuous arm movement task using multielectrode arrays.
  • Analyzing the correlation between single neuron firing and movement parameters.
  • Assessing the predictability of arm movements from neuronal ensemble activity.

Related Experiment Videos

Main Results:

  • Significant variability in individual neuron firing properties was observed.
  • Despite nonstationary correlations, stable predictions of arm movements were achievable from neuronal ensemble activity.
  • Evidence supports redundant encoding of movement parameters in the motor cortex.

Conclusions:

  • Motor cortex utilizes redundant encoding, allowing for flexible neural network function.
  • Accurate brain-machine interfaces require recording from large neuronal ensembles to ensure stable performance over time.