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Related Experiment Videos

[Oligodendrogliomas and radiosurgery].

J-J Lemaire1, T Khalil, J-J Bard

  • 1Service de Neurochirurgie A, CHU, Clermont-Ferrand. jjlemaire@chu-clermontferrand.fr

Neuro-Chirurgie
|November 18, 2005
PubMed
Summary
This summary is machine-generated.

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Radiosurgery offers transitional local control for recurrent malignant gliomas and select benign gliomas. Precise target definition and further studies are crucial for optimizing its use in glioma treatment.

Area of Science:

  • Neurosurgery
  • Radiation Oncology
  • Oncology

Context:

  • Oligodendroglioma radiosurgery requires integration into broader glioma treatment strategies.
  • Current indications for radiosurgery in gliomas are primarily for recurrent malignant forms as a second-line therapy.
  • It may exceptionally be used for small, surgically inaccessible benign gliomas.

Purpose:

  • To evaluate the role and efficacy of radiosurgery in managing oligodendrogliomas and other gliomas.
  • To define the current practice and limitations of radiosurgery for glioma treatment.
  • To highlight areas for future research, including target definition and prospective studies.

Summary:

  • Radiosurgery provides transitional local control for malignant gliomas, typically as a second-line treatment upon recurrence, with doses around 15-18 Gy.

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  • It can be exceptionally applied to small, benign gliomas unsuitable for open surgery.
  • Accurate definition of glioma boundaries, especially for malignant types, remains a challenge, with contrast-enhanced areas often used as the target.
  • Patient selection is critical, favoring those with minimal disability.

    • Impact:

    • Radiosurgery can achieve temporary local control of gliomas, offering clinical and radiological benefits.
    • Improved neuroimaging and target definition are essential for refining radiosurgery indications.
    • Prospective randomized studies are needed to clarify optimal use and patient selection for radiosurgery in glioma management.