Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Correction to: pH control and the production of extracellular dextransucrase by Leuconostoc mesenteroides.

World journal of microbiology & biotechnology·2020
Same author

Libyan Thymus capitatus essential oil: antioxidant, antimicrobial, cytotoxic and colon pathogen adhesion-inhibition properties.

Journal of applied microbiology·2015
Same author

pH control and the production of extracellular dextransucrase byLeuconostoc mesenteroides.

World journal of microbiology & biotechnology·2014
Same author

Ultrasound-assisted adsorption of 4-dodecylbenzene sulfonate from aqueous solutions by corn cob activated carbon.

Ultrasonics sonochemistry·2012
Same author

Ultrasound-assisted adsorption of copper(II) ions on hazelnut shell activated carbon.

Ultrasonics sonochemistry·2009
Same author

[Characterization and antimicrobial activity of the bioactive metabolites in streptomycete isolates].

Mikrobiologiia·2007

Related Experiment Video

Updated: Jun 25, 2026

A Straightforward Method for Glucosinolate Extraction and Analysis with High-pressure Liquid Chromatography (HPLC)
10:09

A Straightforward Method for Glucosinolate Extraction and Analysis with High-pressure Liquid Chromatography (HPLC)

Published on: March 15, 2017

Kinetics of ultrasonic extraction of extractive substances from garden (Salvia officinalis L.) and glutinous (Salvia

D T Velicković1, D M Milenović, M S Ristić

  • 1Zdravlje-Actavis, Vlajkova 199, 16000 Leskovac, Serbia and Montenegro. veljkovicb@yahoo.com

Ultrasonics Sonochemistry
|November 19, 2005
PubMed
Summary

Ultrasonic extraction of extractive substances (ES) from sage herbs is a two-step process. Higher solvent polarity and approximately 20 minutes of extraction optimize ES yield.

More Related Videos

Employing Pressurized Hot Water Extraction (PHWE) to Explore Natural Products Chemistry in the Undergraduate Laboratory
09:48

Employing Pressurized Hot Water Extraction (PHWE) to Explore Natural Products Chemistry in the Undergraduate Laboratory

Published on: November 7, 2018

Ultrasonic-Assisted Extraction of Cannabidiolic Acid from Cannabis Biomass
05:46

Ultrasonic-Assisted Extraction of Cannabidiolic Acid from Cannabis Biomass

Published on: May 27, 2022

Related Experiment Videos

Last Updated: Jun 25, 2026

A Straightforward Method for Glucosinolate Extraction and Analysis with High-pressure Liquid Chromatography (HPLC)
10:09

A Straightforward Method for Glucosinolate Extraction and Analysis with High-pressure Liquid Chromatography (HPLC)

Published on: March 15, 2017

Employing Pressurized Hot Water Extraction (PHWE) to Explore Natural Products Chemistry in the Undergraduate Laboratory
09:48

Employing Pressurized Hot Water Extraction (PHWE) to Explore Natural Products Chemistry in the Undergraduate Laboratory

Published on: November 7, 2018

Ultrasonic-Assisted Extraction of Cannabidiolic Acid from Cannabis Biomass
05:46

Ultrasonic-Assisted Extraction of Cannabidiolic Acid from Cannabis Biomass

Published on: May 27, 2022

Area of Science:

  • Phytochemistry
  • Chemical Engineering
  • Pharmacognosy

Background:

  • Sage (Salvia officinalis L. and Salvia glutinosa L.) contains valuable extractive substances (ES).
  • Traditional extraction methods can be time-consuming and less efficient.
  • Ultrasonic extraction offers a potentially faster and more effective approach.

Purpose of the Study:

  • To investigate the kinetics and mechanism of ultrasonic extraction of ES from two sage species.
  • To determine the optimal conditions for maximizing ES yield and analyze extract composition.
  • To mathematically model the ultrasonic extraction process.

Main Methods:

  • Ultrasonic extraction of dry sage herbs using petroleum ether, 70% ethanol, and water at 40°C.
  • Analysis of the kinetics and composition of the resulting dry extracts.
  • Mathematical modeling using unsteady diffusion, film theory, and the Ponomaryov equation.

Main Results:

  • Ultrasonic extraction proceeds in two stages: surface dissolution (washing) followed by internal diffusion (slow extraction).
  • Extractive substance (ES) yield increases with solvent polarity (water > ethanol > petroleum ether).
  • Near-maximal ES concentration is achieved within approximately 20 minutes of extraction.
  • Extract composition is influenced by solvent polarity, extraction time, and sage species.

Conclusions:

  • Ultrasonic extraction is an efficient method for obtaining extractive substances from sage.
  • Solvent polarity and extraction time are critical parameters for optimizing yield and composition.
  • The two-step mechanism and mathematical models provide a framework for understanding and improving the process.