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Diffusely calcified renal cell carcinoma: CT features.

H Onitsuka1, J Murakami, S Naito

  • 1Department of Radiology, Faculty of Medicine, Kyushu University, Fukuoka, Japan.

Journal of Computer Assisted Tomography
|July 1, 1992
PubMed
Summary
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Diffuse calcification in renal masses is rare. This study details an unusual case of clear cell renal cell carcinoma exhibiting diffuse calcification within tumor cells, challenging typical presentations.

Area of Science:

  • Nephrology
  • Oncology
  • Radiology

Background:

  • Renal mass calcifications are typically focal and punctate.
  • Diffuse calcification within renal masses is exceptionally rare.
  • Standard calcified renal cell carcinomas are often hypovascular.

Observation:

  • A renal neoplasm presented with diffuse calcification on CT imaging.
  • Angiography revealed intermediate vascularity.
  • Histological examination confirmed clear cell renal cell carcinoma.

Findings:

  • The renal cell carcinoma displayed numerous calcific deposits within tumor cells.
  • This presentation deviates from the usual interstitial calcification pattern.
  • The tumor showed intermediate vascularity, unlike typically hypovascular calcified tumors.

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Implications:

  • This case expands the understanding of renal cell carcinoma imaging and histological variations.
  • It highlights the importance of considering rare presentations in renal mass diagnosis.
  • Further research may clarify the mechanisms and clinical significance of diffuse intra-tumoral calcification.