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Updated: Aug 14, 2026

A Computational Modeling Approach to Investigate the Influence of Hyperthermia on the Tumor Microenvironment
Published on: December 1, 2023
[The simulation of SAR and temperature distribution and parameters analysis for tumor RF thermotherapy]
1Thermal Energy Department, Tianjin University, Tianjin 300072, China. zn-zhao@sina.com
Abstract:
In this paper are reported the model establishment and numerical simulation of specific absorption rate(SAR) and the unsteady temperature distribution for the non-invasive tumor RF thermotherapy. The model can correctly reflect the attenuation of electromagnetic wave in the biotissue, the variation of perfusion with temperature and lower perfusion of the tumor tissue are fully considered in the simulation. These measures made simulation results more close to the clinical results. Also presented in the paper are detailed analyses and discussions on the characteristics of SAR of electromagnetic energy and the temperature profiles, the effects of the frequency and the perfusion on the depth for effective treatment. The simulation results are of great significance for directing the clinical application of tumor RF thermotherapy.
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