Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[A study on myocardial microcirculation with coronary angiographic impulse response function].

Xingxin Chen1, Bingquan Luo, Lei Yue

  • 1China University of Mine and Technique, Xuzhou 221008, China.

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi = Journal of Biomedical Engineering = Shengwu Yixue Gongchengxue Zazhi
|November 22, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Zoledronic acid in the treatment of severe scoliosis associated with neurofibromatosis type 1 (NF1): a case report.

Annals of medicine and surgery (2012)·2026
Same author

Efficacy of endoscopic removal of anterior malleolar ligament calcification combined with tympanic membrane repair for the treatment of conductive hearing loss.

Pakistan journal of medical sciences·2026
Same author

[Early transcriptomic features of neutrophils and monocytes activated by the outer membrane protein MSP2 of anaplasma phagocytophilum].

Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology·2026
Same author

MARVELD1 regulates hepatocyte transformation via maintaining NF-κB signaling homeostasis mediated by the CCL5/CCR5 axis between hepatic stellate cells and hepatocytes.

Cell communication and signaling : CCS·2026
Same author

The association between physical activity and sleep quality in college students: A multiple mediation analysis based on physical activity enjoyment and negative emotions.

Acta psychologica·2026
Same author

Sleep problems and emotional and behavioral problems among adolescents: examining independent types, cumulative scores, and latent patterns.

Child and adolescent psychiatry and mental health·2026

A new digital coronary angiograph analysis system helps evaluate coronary stenosis. The system, using coronary angiographic impulse response, correlates microcirculation (Tmicro(-1)) with minimal stenotic diameter (MLD), aiding diagnosis.

Area of Science:

  • Cardiology
  • Medical Imaging
  • Physiology

Background:

  • Coronary artery disease diagnosis relies on anatomical and physiological assessments.
  • Quantitative coronary analysis (QCA) provides anatomical stenosis information.
  • Evaluating coronary microcirculation and hemodynamics is crucial for comprehensive assessment.

Purpose of the Study:

  • To establish and validate a digital coronary angiograph-analyzing system based on coronary angiographic impulse response.
  • To investigate the relationship between coronary microcirculation (Tmicro(-1)), minimal stenotic diameter (MLD), and hemodynamic parameters.
  • To assess the system's utility in diagnosing coronary lesions in conjunction with QCA.

Main Methods:

  • Development of a digital coronary angiograph-analyzing system using coronary angiographic impulse response.

Related Experiment Videos

  • Integration of the system with quantitative coronary analysis (QCA).
  • Analysis of coronary microcirculation (Tmicro(-1)), minimal stenotic diameter (MLD), mean arterial pressure (mAP), coronary flow velocity (CFV), and coronary resistance (Rcor) in 20 patients.

    • Main Results:

    • Minimal stenotic diameter (MLD) and Tmicro(-1) decreased with increased proximal coronary stenosis.
    • Following percutaneous coronary intervention, Tmicro(-1) increased with MLD.
    • A significant linear correlation was found between Tmicro(-1) and MLD (r = 0.87, P < 0.001).

    Conclusions:

    • The Tmicro(-1) index, derived from the digital coronary angiographic impulse response analysis system, aids in evaluating coronary lesions.
    • Integration with CFV and QCA provides a comprehensive anatomical and physiological diagnosis.
    • The system facilitates integrated assessment of both macro and microcirculation in coronary lesions.