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Diabetes mellitus and candidiases.
1Department of Epidemiology, Faculty of Medicine, Safárik University, Kosice, Slovakia. erikdorco@pobox.sk
Folia Microbiologica
|November 22, 2005
Summary
Diabetic patients frequently develop fungal infections, particularly Candida albicans, affecting various body sites including the mouth, urinary tract, and skin lesions. This study highlights the prevalence of Candida species in individuals with diabetes mellitus.
Area of Science:
- Mycology
- Diabetology
- Infectious Diseases
Background:
- Diabetes mellitus is a chronic condition associated with increased susceptibility to infections.
- Fungal infections, particularly those caused by Candida species, are a known complication in diabetic patients.
- Understanding the spectrum of Candida infections in different diabetic clinical states is crucial for effective management.
Purpose of the Study:
- To investigate the prevalence and types of Candida species infections in patients with diabetes mellitus.
- To identify specific Candida species associated with various clinical manifestations in diabetic individuals.
- To correlate Candida infections with different clinical states of diabetes mellitus.
Main Methods:
- Patients diagnosed with diabetes mellitus were screened for fungal infections.
- Samples were collected from various sites including urine, oral cavity, nails, skin lesions, ears, and eyes.
- Fungal identification was performed using cultivation on Sabouraud agar and CHROMagar Candida, along with saccharide assimilation tests.
Main Results:
- Candida species were detected in multiple sample types from diabetic patients.
- Candida albicans was the most frequently isolated species across various infections, including oral candidiasis, urinary tract infections, and leg ulcers.
- Other Candida species like C. parapsilosis, C. tropicalis, C. krusei, C. guilliermondii, and C. robusta were also identified in different clinical contexts.
Conclusions:
- Diabetic patients exhibit a high prevalence of Candida infections affecting diverse anatomical sites.
- Candida albicans is the predominant fungal pathogen in this population, associated with numerous clinical conditions.
- The findings underscore the importance of monitoring for and managing fungal infections in individuals with diabetes mellitus.
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