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Updated: Aug 14, 2026

Bone Marrow Transplantation Platform to Investigate the Role of Dendritic Cells in Graft-versus-Host Disease
Published on: March 17, 2020
[Graft-versus-host-like flexural eruption after autologous stem cell transplantation]
Helge Riemann1, Michael Thomas, Dieter Metze
1Hautklinik, Universitätsklinikum Münster.
Abstract:
A 29-year-old man received an autologous stem cell transplantation after myeloablation with busulfan and cyclophosphamide to treat his acute myeloid leukemia, a. Five days after retransfusion of stem cells, hyperpigmented, scaly lesions with occasional perpheral lichenoid papules developed in groins, axillae, genitalia, and elbows. Histology revealed a graft-versus-host-like reaction. Although the graft-versus-host reaction, by definition, requires allogeneic cells, similar lesions have been reported after autologous stem cell transplantation. The clinical course is usually mild and self-limited. Flexural graft-versus-host-like reactions after autologous stem cell transplantation have been reported in four patients.
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