Related Experiment Videos
The calcium antagonists in vasospastic angina
1University of Miami, Division of Cardiology, Miami, FL 33101, USA.
Journal of Cardiovascular Pharmacology
|January 1, 1991
Summary
Calcium antagonists are the primary treatment for vasospastic angina. Amlodipine, a long-acting calcium antagonist, shows promise as a well-tolerated and effective option for managing this condition.
Area of Science:
- Cardiology
- Pharmacology
Background:
- Coronary vasospasm is a key cause of angina at rest.
- Calcium antagonists are established as the preferred treatment for vasospastic angina due to their vasodilatory properties.
Purpose of the Study:
- To evaluate the efficacy and tolerability of amlodipine in patients with vasospastic angina.
- To assess the potential of amlodipine as a preferred calcium antagonist for this condition.
Main Methods:
- Review of current literature on calcium antagonists for vasospastic angina.
- Analysis of preliminary evidence regarding amlodipine's use in vasospastic angina.
Main Results:
- Most available calcium antagonists are effective and safe for vasospastic angina.
- Amlodipine is a long-acting dihydropyridine suitable for once-daily dosing.
- Preliminary data suggest amlodipine is efficacious and well-tolerated.
Conclusions:
- Amlodipine demonstrates potential as a preferred treatment for vasospastic angina.
- Factors like duration of action and patient compliance are crucial in therapy selection.
- Further evidence supports amlodipine's role in managing vasospastic angina.