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Assessment of Vascular Function in Patients With Chronic Kidney Disease
08:50

Assessment of Vascular Function in Patients With Chronic Kidney Disease

Published on: June 16, 2014

Italian audit on therapy of hypertension in chronic kidney disease: the TABLE-CKD study

Luca De Nicola1, Roberto Minutolo, Pasquale Zamboli

  • 1Division of Nephrology, Second University of Naples, Naples, Italy. luca.denicola@unina2.it

Seminars in Nephrology
|November 22, 2005
PubMed

Insights

Achieving target blood pressure is crucial for preventing cardiovascular disease in patients with chronic kidney disease (CKD). However, hypertension management in CKD patients is suboptimal, with less than 20% reaching their blood pressure goals.

Area of Science:

  • Nephrology
  • Cardiology
  • Hypertension Management

Background:

  • Essential hypertension management guidelines recommend target blood pressure levels to prevent cardiovascular disease.
  • Chronic kidney disease (CKD) patients face a significantly higher risk of cardiovascular events, necessitating stricter blood pressure control than the general population.
  • Despite the critical need, hypertension management in CKD patients is often suboptimal.

Purpose of the Study:

  • To assess the prevalence of patients achieving target blood pressure levels in a cohort of Italian individuals with mild to advanced CKD.
  • To evaluate current antihypertensive strategies in CKD patients and identify areas for improvement.

Main Methods:

  • The study involved Italian patients with mild to advanced CKD under regular nephrologist care.
  • Data on blood pressure control and antihypertensive strategies were collected and analyzed.

Main Results:

  • Less than 20% of CKD patients in the study achieved target blood pressure levels.
  • The findings suggest that current antihypertensive strategies are not optimal for this high-risk population.
  • A significant salt sensitivity of blood pressure was noted in this CKD population.

Conclusions:

  • Hypertension control remains a significant challenge in CKD patients, with a low prevalence of individuals at target blood pressure.
  • There is a clear need to optimize antihypertensive strategies in CKD.
  • More aggressive management of volume expansion may improve blood pressure control, considering the high salt sensitivity in this population.

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