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Updated: Aug 14, 2026
Flash NanoPrecipitation for the Encapsulation of Hydrophobic and Hydrophilic Compounds in Polymeric Nanoparticles
Published on: January 7, 2019
Micro- and nanoparticulates
Andrew A Moshfeghi1, Gholam A Peyman
1Bascom Palmer Eye Institute, 900 NW 17th St Miami, FL 33136, USA. amoshfeghi@med.miami.edu
Objectives:
Pharmacotherapeutics has begun to play an increasingly important role in the management of patients with neovascular age-related macular degeneration (AMD). Because micro- and nano-particulates are currently being evaluated as a potential drug-delivery option for AMD patients, the purpose of this analysis was to describe how micro- and nano-particulates have been used experimentally and what their potential clinical applications may be.
Findings:
Micro- and nano-particulates have been used primarily on a pre-clinical basis as new drug-delivery devices in experimental models of neovascular AMD.
Conclusions:
It is likely that micro- and nano-particulates will become an important component of targeted clinical pharmacotherapeutics in patients with neovascular AMD.
