Cardiovascular risk assessment scoring system for the determination of cardiovascular mortality in renal transplant

A Gupta1, C Wroe, H Mi

  • 1Department of Renal and Liver Transplant, The Freeman Hospital, High Heaton, Newcastle Upon Tyne NE7 7DN, UK. ajaygupta21@hotmail.com

Transplantation Proceedings
|November 22, 2005
PubMed

Insights

Cardiovascular disease is the leading cause of death after kidney transplants. A modified cardiac risk assessment accurately predicted survival rates in transplant patients, identifying higher risks in those who died.

Area of Science:

  • Nephrology
  • Cardiology
  • Transplantation Science

Background:

  • Cardiovascular disease (CVD) is the primary cause of mortality following renal transplantation.
  • Effective risk stratification is crucial for managing post-transplant outcomes.

Purpose of the Study:

  • To evaluate a modified cardiac risk assessment system in renal transplant recipients.
  • To determine the correlation between cardiac risk scores and patient survival post-transplant.

Main Methods:

  • A modified cardiac risk assessment tool was applied retrospectively.
  • Renal transplant patients were categorized into deceased and survived groups.
  • Cardiac risk scores were compared between the groups.

Main Results:

  • A significant correlation was observed between low, medium, and high cardiac risk scores and patient survival.
  • The group of patients who died post-transplant exhibited significantly higher cardiovascular risk scores compared to controls.

Conclusions:

  • The modified cardiac risk assessment system demonstrates good predictive value for survival in renal transplant recipients.
  • Higher cardiovascular risk scores are associated with increased mortality in this patient population.

Related Concept Videos

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
Drug Dosing in Renal Diseases: Estimation of Glomerular Filtration Rate Based on Serum Creatinine Concentration01:28

Drug Dosing in Renal Diseases: Estimation of Glomerular Filtration Rate Based on Serum Creatinine Concentration

Glomerular filtration rate (GFR) can be estimated from serum creatinine using the modification of diet in renal disease (MDRD) formula or the chronic kidney disease–epidemiology collaboration (CKD–EPI) equation. Both methods are widely used in clinical practice to assess kidney function and guide treatment decisions.The MDRD equation does not require weight or height measurements and is normalized to the body surface area of 1.73 m², considered the average adult surface area. This equation is...
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Continuous Renal Replacement Therapy01:30

Continuous Renal Replacement Therapy

Continuous Renal Replacement Therapy, also known as CRRT, is a procedural treatment for acute kidney injury (AKI) that gradually removes uremic toxins and fluids while maintaining acid-base balance and stabilizing electrolytes. It is particularly useful for hemodynamically unstable patients. Unlike intermittent hemodialysis, which is faster, CRRT provides a gentler approach over 24 hours, closely mimicking the function of natural kidneys. However, CRRT is not ideal for patients with...
Assessment of the Cardiovascular System I: Subjective Data01:23

Assessment of the Cardiovascular System I: Subjective Data

A thorough health history and physical assessment are essential for identifying cardiovascular disease (CVD) symptoms and distinguishing them from other health issues.
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...