Related Experiment Video
Updated: Aug 14, 2026
06:33
Genetic Analysis of Hereditary Transthyretin Ala97Ser Related Amyloidosis
Published on: June 9, 2018
Osteonecrosis of the metacarpal head in a patient with a prothrombin 20210A gene mutation
Anders Björkman1, Peter Jörgsholm, Isabella M Burtscher
1Department of Hand Surgery, University Hospital Malmö, Malmö, Sweden. anders.bjorkman@hand.mas.lu.se
Abstract:
Osteonecrosis of the metacarpal head is rare and of unknown cause. We describe a 17-year-old girl with osteonecrosis of the fourth metacarpal head and a mutated prothrombin 20210A gene, which suggests a possible relation between a hypercoagulable state and osteonecrosis of the metacarpal head.
