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Updated: Aug 14, 2026

Organ Ischemia-Reperfusion Injury by Simulating Hemodynamic Changes in Rat Liver Transplant Model
Published on: March 6, 2021
A case of post-reperfusion syndrome following surgery for liver trauma
S K Kodakat1, R Ginsburg, P B Gopal
1Department of Anaesthetics, King's College Hospital, Denmark Hill, London SE5 9RS, UK.
Abstract:
We report the case of a young trauma patient who needed tight perihepatic surgical packing to control bleeding from a ruptured liver. He developed severe cardiovascular and respiratory decompensation on removal of the surgical packs as a result of the post-reperfusion syndrome. He underwent a total hepatectomy and, 35 h later, orthotopic liver transplantation. The pathophysiology of post-reperfusion syndrome is discussed, and its importance to anaesthetists in the non-transplant setting is emphasized.

