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Assessing Teratogenic Changes in a Zebrafish Model of Fetal Alcohol Exposure
Published on: March 20, 2012
Fetal alcohol syndrome: anthropometric and oral health status
Sudeshni Naidoo1, Usuf Chikte, Ria Laubscher
1Department of Community Oral Health, University of Western Cape, Tygerberg, South Africa. suenaldoo@uwc.ac.za
Abstract:
The purpose of this study was to analyze the anthropometric measures and oral health status of children with fetal alcohol syndrome (FAS) and compare them to matched controls. The sample of 90 cases (children diagnosed with FAS) and 90 controls were matched for age, gender, and social class. The mean age of the cases was 8.9 years with the controls slightly older at 9.1 years. The results of the anthropometric measurements in respect of weight, height, and head circumference showed significantly lower values for the FAS children when compared to the controls. Several physical abnormalities described in children with FAS were seen in this study. Some of these abnormalities seen in the FAS children included deformities in the small joints of the hand, altered palmar creases, and malformation of the ears. The prevalence of enamel opacities between FAS and controls was not significantly different and averaged around 15% for both groups. More than three quarters of both the cases and the controls demonstrated the presence of plaque and almost two-thirds demonstrated gingival bleeding on probing. FAS patients had statistically significantly (p<0.001) more dentofacial anomalies than the controls. The mean decayed, missing, and filled teeth (dmft) score for the FAS sample was slightly higher, though not significantly different from that of the controls, and the decayed component (d) made up the largest part of the index in both groups.
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