[A comparative study of changes in suture materials in mammary gland tissues]

In the experiment on 75 white rats, the reactogenicity and strength of catgut, dexon, kacelon and PGL (native analogue of vicryl) were studied 10, 20 and 30 days after their implantation into parenchyma of the lactating mammary gland (MG). Around a catgut thread, the cellular-tissue reaction according to the type of purulent inflammation occurred. A danger of oncogenic effect of catgut which manifested itself in proliferation and atypical hyperplasia of epithelium of the MG ducts was noted. Dexon, kacelon and PGL were characterized by similar low reactogenicity, but kacelon strength reduced considerably in moistening. Dexon and PGL due to their reactogenicity and strength properties are the materials of choice in surgical treatment of MG diseases.