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Antimicrobial resistance of Escherichia coli O157 from cattle in Korea

Ju-Yeon You1, Bo-Mi Moon, In-Gyeong Oh

  • 1Veterinary Public Health, College of Veterinary Medicine, Chonbuk National University, Chonju, 561-756, Republic of Korea.

International Journal of Food Microbiology
|November 23, 2005
PubMed

Insights

Many cattle feces Escherichia coli O157 isolates in Korea show high antimicrobial resistance. A significant portion possess virulence genes, suggesting potential human disease risk.

Area of Science:

  • Veterinary Microbiology
  • Food Safety
  • Public Health

Background:

  • Escherichia coli O157 is a significant foodborne pathogen.
  • Antimicrobial resistance in E. coli O157 poses a public health threat.
  • Understanding resistance patterns is crucial for risk assessment.

Purpose of the Study:

  • To investigate antimicrobial resistance patterns in Escherichia coli O157 isolates from Korean cattle feces.
  • To identify the prevalence of virulence markers in resistant isolates.
  • To assess the potential public health implications of resistant E. coli O157.

Main Methods:

  • Isolation and antimicrobial susceptibility testing of 45 E. coli O157 from cattle feces.
  • Analysis of resistance to multiple antibiotics, including streptomycin, tetracycline, and sulfisoxazole.
  • Polymerase chain reaction (PCR) to detect Shiga toxin genes (stx1, stx2).

Main Results:

  • 32 out of 45 isolates (71%) were resistant to at least one antibiotic.
  • 28 isolates (62%) exhibited resistance to four or more antibiotics.
  • Resistance to streptomycin (32), tetracycline (30), and sulfisoxazole (30) was common.
  • Two isolates showed resistance to fluoroquinolones and over 10 other agents.
  • 25 resistant isolates tested positive for stx1 and/or stx2 virulence genes.

Conclusions:

  • A high prevalence of multidrug-resistant Escherichia coli O157 was found in cattle feces.
  • The presence of Shiga toxin genes in resistant isolates indicates a potential zoonotic risk.
  • These findings highlight the need for surveillance and control measures to mitigate public health risks.

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