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Updated: Aug 14, 2026

Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy
Published on: September 20, 2024
H2(15)O or 13NH3 PET and electromagnetic tomography (LORETA) during partial status epilepticus
D Zumsteg1, R A Wennberg, V Treyer
1Krembil Neuroscience Centre, Toronto Western Hospital, University of Toronto, Toronto, ON M5T 2S8, Canada. dzumsteg@uhnres.utoronto.ca
Abstract:
The authors evaluated the feasibility and source localization utility of H2(15)O or 13NH3 PET and low-resolution electromagnetic tomography (LORETA) in three patients with partial status epilepticus (SE). Results were correlated with findings from intraoperative electrocorticographic recordings and surgical outcomes. PET studies of cerebral blood flow and noninvasive source modeling with LORETA using statistical nonparametric mapping provided useful information for localizing the ictal activity in patients with partial SE.
