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Updated: Aug 13, 2026
Early Detection of Cyanobacterial Blooms and Associated Cyanotoxins using Fast Detection Strategy
Published on: February 25, 2021
Analysis of cyanobacterial-derived saxitoxins using high-performance ion exchange chromatography with chemical
John Papageorgiou1, Brenton C Nicholson, Thomas A Linke
1Australian Water Quality Centre, South Australian Water Corporation, Salisbury, South Australia, 5108, Australia. john.papageorgiou@sawater.com.au
Abstract:
A single run HPLC method utilizing ion exchange as the separation mode with a novel mobile phase system coupled to chemical postcolumn oxidation and fluorescence detection has been developed and demonstrated to be applicable to the quantitative analysis of paralytic shellfish poisons (PSPs) produced by Australian cyanobacteria (Anabaena circinalis) and other cyanobacteria. Both the cyanobacterial matrix and natural water constituents did not significantly affect the performance of this method. The daily precision of this method was adequate for it to be considered as a routine analytical tool for direct PSP analysis (prePSP concentration is not required) of cyanobacterial extracts and water bodies containing PSPs (C1, C2, GTX2, GTX3, NEO, STX) in the low parts per billion concentration range (10-70 ppb).
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