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Updated: Aug 14, 2026

A High Throughput, Multiplexed and Targeted Proteomic CSF Assay to Quantify Neurodegenerative Biomarkers and Apolipoprotein E Isoforms Status
Published on: October 20, 2016
A new route to non invasive diagnosis in neurodegenerative diseases?
Timoteo Carletti1, Duccio Fanelli, Alessio Guarino
1Département des Mathématiques FUNDP, rempart de la vierge, 8, B 5000 Namur, Belgique. timoteo.carletti@fundp.ac.be
Abstract:
We propose a simple dynamical system to interpret the gait time series from patients affected by three neurodegenerative diseases: Parkinson, Huntington and Amyotrophic Lateral Sclerosis. The model is shown to reproduce the main aspects of the experimental time series. Within this scenario, quantitative differences in specific indicators are detected thus opening up the perspective for innovative, non invasive, diagnosis procedures from direct measurements of gait dynamics.

