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Development of an In Vitro Ocular Platform to Test Contact Lenses
Published on: April 6, 2016
Disinfecting action of a new multi-purpose disinfection solution for contact lenses
R A Rosenthal1, W M Bell, R Abshire
1Alcon Research Ltd, Fort Worth, TX 76134-2099, USA.
Abstract:
The disinfection activity of a new multipurpose disinfection solution (OPTI-FREE Express with ALDOX) was compared to several other contact lens disinfecting solutions. The new solution is preserved with polyquaternium-1 and myristamidopropyl dimethylamine. The other solutions included 3% hydrogen peroxide systems and multipurpose solutions (MPS) preserved with polyhexamethylene biguanide. The products were tested for antimicrobial activity against Staphylococcus spp., Pseudomonas aeruginosa, Serratia marcescens, Candida albicans, Fusarium solani, and Aspergillus fumigatus. OPTI-FREE Express provided a broader range of antimicrobial activity than the MPS. It provided activity similar to that demonstrated by 3% hydrogen peroxide systems, but unlike the hydrogen peroxide system tested, it also prevented re growth of the organisms during extended storage.
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