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Updated: Jul 26, 2026

Development of an In Vitro Ocular Platform to Test Contact Lenses
Published on: April 6, 2016
Bandage soft contact lens barrier function: a clinical research note.
M R Lattimore1, S S Schallhorn, R B Lewis
1U.S. Army Aeromedical Research Laboratory, Fort Rucker, AL, USA. Morris.Lattimore@det.amedd.army.mil
Bandage soft contact lenses prevent corneal swelling after laser surgery. Retained lenses maintained normal corneal thickness, while lost lenses led to edema, highlighting their protective fluid barrier function.
Area of Science:
- Ophthalmology
- Biomedical Engineering
Background:
- Corneal thickness is critical for refractive surgery outcomes.
- Diurnal variations can affect corneal thickness measurements.
- Bandage contact lenses are used post-operatively for protection.
Purpose of the Study:
- To investigate the effect of bandage soft contact lenses on post-operative corneal thickness.
- To determine if lens displacement influences corneal hydration.
- To elucidate the role of bandage lenses in preventing corneal edema.
Main Methods:
- Corneal thickness was measured pre- and post-operatively in 18 subjects undergoing laser refractive surgery.
- Measurements accounted for diurnal variations.
- Subjects were categorized based on retention or loss of overnight bandage lenses.
Main Results:
- Subjects who lost bandage lenses showed uniformly thick, swollen corneas (edema).
- Subjects who retained bandage lenses maintained a stable corneal thickness profile.
- Reapplication of bandage lenses in affected subjects normalized corneal thickness by day 2.
Conclusions:
- Bandage soft contact lenses provide a crucial fluid barrier, preventing corneal edema.
- This barrier function supports the corneal endothelial pump in managing fluid balance.
- The findings explain the efficacy of bandage lenses in managing conditions like corneal bullous.
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