Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Grading of corneal transparency.

Clare O'Donnell1, James S Wolffsohn

  • 1Department of Optometry and Neuroscience, UMIST, PO Box 88, Manchester M60 1QD, UK. clare.odonnell@umist.ac.uk

Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association
|November 24, 2005
PubMed
Summary

Objective image analysis of corneal transparency shows intensity variation across a corneal section is the best indicator of corneal edema. This method, using a slit-lamp camera, offers a reliable way to assess corneal edema, especially compared to pupil-based techniques.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effect of combining peripheral defocus spectacle lens wear with 0.01% atropine.

Annals of translational medicine·2026
Same author

Pulmonary Hypertension in Adults With a Systemic Right Ventricle (Biventricular Circulation).

JACC. Advances·2026
Same authorSame journal

The answer is 23 years - what is the question? Understanding the time lag between ophthalmic research and clinical adoption.

Contact lens & anterior eye : the journal of the British Contact Lens Association·2026
Same author

Effect of a head strap on the function of an eyelid warming compress.

Contact lens & anterior eye : the journal of the British Contact Lens Association·2026
Same author

Diagnostic utility of inflammation-associated clinical signs in detecting MMP-9 expression in dry eye disease: A cross-sectional conjunctival impression cytology and droplet digital PCR study.

Contact lens & anterior eye : the journal of the British Contact Lens Association·2026
Same author

Optimising slit-lamp biomicroscope fluorescein imaging filters.

Contact lens & anterior eye : the journal of the British Contact Lens Association·2026

Area of Science:

  • Ophthalmology
  • Biomedical Engineering
  • Corneal Imaging

Background:

  • Assessing corneal transparency is crucial for diagnosing and managing various eye conditions.
  • Current methods for grading corneal transparency lack widespread clinical adoption.
  • Objective image analysis offers a potential for standardized and reproducible assessment.

Purpose of the Study:

  • To review existing literature on corneal transparency grading.
  • To evaluate the efficacy of objective image analysis for assessing corneal edema.
  • To identify the most reliable parameters for objective corneal transparency assessment.

Main Methods:

  • Systematic review of academic literature on corneal transparency grading.
  • Objective analysis of corneal edema grading scales (Annunziato, Efron, Vistakon-Synoptik).

Related Experiment Videos

  • Experimental induction of corneal edema using low oxygen transmissibility contact lenses and monitoring recovery via pachymetry, visual acuity, and image analysis.

    • Main Results:

    • No single corneal transparency grading method is universally adopted in clinical practice.
    • Objective image analysis, particularly intensity variation across a corneal section, strongly correlates with corneal thickness and edema.
    • Pupil image scales correlate with average intensity, while corneal section scales correlate with intensity variation.

    Conclusions:

    • Intensity variation across a corneal section is the most effective objective measure for determining corneal edema.
    • Slit-lamp camera connected to a computer can facilitate this objective measurement.
    • Sclerotic scatter illumination techniques are less effective for assessing corneal edema over the pupil area, particularly with soft contact lens wear.