Related Experiment Video
Updated: Jul 18, 2026

Practical Considerations in Studying Metastatic Lung Colonization in Osteosarcoma Using the Pulmonary Metastasis Assay
Published on: March 12, 2018
Imaging of metastatic orbital leiomyosarcoma
Gerasimos M Voros1, Daniel Birchall, Thomas Ressiniotis
1Department of Ophthalmology, Royal Victoria Infirmary, Newcastle Upon Tyne, United Kingdom. gvorosgr@doctors.org.uk
A rare case of metastatic orbital leiomyosarcoma in a 74-year-old man was diagnosed using orbital imaging. Surgical removal and pathological examination confirmed the metastatic soft tissue tumor.
Area of Science:
- Ophthalmology
- Oncology
- Radiology
Background:
- Orbital tumors are rare, and metastatic disease to the orbit presents unique diagnostic challenges.
- Leiomyosarcoma, a malignant mesenchymal tumor, typically arises in soft tissues but can metastasize to distant sites.
Observation:
- A 74-year-old male presented with painless proptosis of the left eye.
- Imaging studies including orbital ultrasound, computed tomography (CT), and magnetic resonance imaging (MRI) revealed a large medial orbital mass.
Findings:
- Pathologic examination confirmed the orbital mass as a metastatic orbital leiomyosarcoma.
- The study details the comprehensive imaging characteristics of this rare metastatic tumor.
Implications:
- Integrated use of ultrasound, CT, and MRI is crucial for accurate diagnosis and surgical planning of orbital masses.
- This case highlights the importance of considering metastatic disease in the differential diagnosis of orbital tumors, even in the absence of typical symptoms.
More Related Videos
11:15A Preclinical Mouse Model of Osteosarcoma to Define the Extracellular Vesicle-mediated Communication Between Tumor and Mesenchymal Stem Cells
Published on: May 6, 2018
04:25Intratibial Osteosarcoma Cell Injection to Generate Orthotopic Osteosarcoma and Lung Metastasis Mouse Models
Published on: October 28, 2021