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Menstrual irregularities with excessive blood loss: a clinico-pathological correlation
Muhammad Muzaffar1, Khalida Adeeb Khanum Akhtar, Shahina Yasmin
1Department of Pathology, Islamic International Medical College, Railway Hospital, Rawalpindi.
JPMA. the Journal of the Pakistan Medical Association
|November 25, 2005
Summary
This study found endometrial hyperplasia to be the most common cause of excessive menstrual bleeding in women undergoing dilatation and curettage. Malignancy rates were fortunately very low, indicating D&C is an effective diagnostic tool.
Area of Science:
- Gynecological Pathology
- Reproductive Medicine
Background:
- Menstrual irregularities and excessive blood loss are common gynecological complaints.
- Histopathological evaluation of endometrial curettings aids in diagnosing the underlying causes.
Purpose of the Study:
- To analyze histopathological findings in endometrial curettings from patients with abnormal uterine bleeding.
- To correlate these findings with clinical presentations and patient demographics.
Main Methods:
- A total of 260 endometrial curettings were analyzed.
- Specimens were processed and stained with Hematoxylin and Eosin.
- Dilatation and Curettage (D&C) was the primary procedure.
Main Results:
- The most frequent presentations were menorrhagia (51.9%) and metrorrhagia (35.4%).
- Endometrial hyperplasia was the leading pathology (24.7%), followed by chronic endometritis (13%).
- Endometrial malignancy was rare (0.4%).
Conclusions:
- Dilatation and Curettage (D&C) is an effective diagnostic procedure for abnormal uterine bleeding.
- Endometrial hyperplasia is the primary cause of excessive menstrual bleeding in this cohort.
- The low incidence of endometrial cancer is reassuring.
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