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Updated: Aug 14, 2026

Systems Biology of Metabolic Regulation by Estrogen Receptor Signaling in Breast Cancer
Published on: March 17, 2016
[New biochemical and molecular aspects of estrogen's action]
Alejandro D Teppa Garrán1, José Terán Dávila
1Departamento de Andrología, Clínica El Avila, Caracas, Venezuela.
Abstract:
Estrogens have several biologic actions. The specific nuclear actions of estrogens are determined by the hormone structure, the isoform subtype of the involved estrogen receptor, the characteristics of the target gene promoter, and the balance between coactivator and corepressor proteins that modulate the final transcriptional response of the complex between estrogens and its receptors. In this review we focus on the new biochemical and molecular aspects of the estrogens action.
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