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Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach
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Parallel, solution phase synthesis of dihydropyridine miticides via a versatile multicomponent reaction

K Cottrell1, C W Holyoke, M Kline

  • 1DuPont Crop Protection, Stine-Haskell Research Center, P. O. Box 30, Newark, DE 19714, USA.

Combinatorial Chemistry & High Throughput Screening
|November 25, 2005
PubMed

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Cycloadditions are one of the most valuable and effective synthesis routes to form cyclic compounds. These are concerted pericyclic reactions between two unsaturated compounds resulting in a cyclic product with two new σ bonds formed at the expense of π bonds. The [4 + 2] cycloaddition, known as the Diels–Alder reaction, is the most common. The other example is a [2 + 2] cycloaddition.
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