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Updated: Aug 14, 2026

Crystallization of Membrane Proteins in Lipidic Mesophases
Published on: March 28, 2011
Crystallization and preliminary X-ray diffraction studies of two myotoxic Lys49-phospholipases A2 complexed with
Juliana I dos Santos1, Agnes A S Takeda, Daniela P Marchi-Salvador
1Departamento de Física e Biofísica, Instituto de Biociências, UNESP, C. P. 510, CEP 18618-000, Botucatu-SP, Brazil.
Abstract:
BnSP-7 and BnSP-6, two Lys49-phospholipase A2 isolated from Bothrops neuwiedi pauloensis snake venom, were co-crystallized with alpha-tocopherol and X-ray diffraction data were collected for both complexes (2.2 and 2.6 A). A new "alternative" quaternary conformation for these two complexes compared with all other dimeric Lys49-PLA2 has been observed.
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