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Updated: Feb 9, 2026

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
Published on: May 26, 2023
Tricuspid valve repair in an infant with multiple obstructive Candida mycetomas
Giovanni Battista Luciani1, Gianluca Casali, Francesca Viscardi
1Division of Cardiac Surgery, University of Verona, Verona, Italy. gbluciani@yahoo.com
Abstract:
Neonatal fungal valve endocarditis is an uncommon and highly lethal disease. The ideal management strategy is still controversial. Current options include antifungal chemotherapy and surgical intervention, the latter being often limited by risks inherent with valve operations in low body weight infants. We present a case of a premature infant with multiple Candida tricuspid valve mycetomas. Eradication of infection was achieved by combined liposomal amphotericin therapy and complex tricuspid valve repair. Indications, technical aspects, and outcome of treatment in infants are reviewed.
Insights
Neonatal fungal valve endocarditis is a rare, lethal condition. Combined antifungal therapy and complex valve repair successfully treated Candida tricuspid valve mycetomas in a premature infant.
Area of Science:
- Neonatology
- Pediatric Cardiology
- Infectious Diseases
Background:
- Neonatal fungal valve endocarditis is a rare but severe condition.
- Management strategies remain debated due to risks in low-birth-weight infants.
Observation:
- A premature infant presented with multiple Candida tricuspid valve mycetomas.
- Fungal endocarditis in neonates poses significant therapeutic challenges.
Findings:
- Successful eradication of Candida infection was achieved through combined therapy.
- Liposomal amphotericin B and complex tricuspid valve repair were utilized.
- This combined approach offers a viable treatment option for neonatal fungal endocarditis.
Implications:
- This case highlights a successful treatment protocol for a rare neonatal condition.
- The findings suggest that combined antifungal and surgical strategies can be effective.
- Further research into optimizing treatment for neonatal fungal valve endocarditis is warranted.
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