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Related Experiment Videos

Image guided tumour ablation.

A R Gillams1

  • 1Department of Medical Imaging, The Middlesex Hospital, Mortimer Street, London, W1T 3AA, UK. a.gillams@medphys.ucl.ac.uk

Cancer Imaging : the Official Publication of the International Cancer Imaging Society
|November 25, 2005
PubMed
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Thermal ablation techniques like radiofrequency ablation (RFA) and microwave ablation are effective for treating liver tumors, including hepatocellular carcinoma (HCC) and liver metastases. These minimally invasive methods offer promising survival rates for patients ineligible for surgery.

Area of Science:

  • Interventional Radiology
  • Oncology
  • Minimally Invasive Surgery

Background:

  • Thermal ablation technologies are utilized for localized tissue destruction.
  • Radiofrequency ablation (RFA) is currently favored, with microwave ablation emerging as a competitor.
  • Percutaneous ethanol injection (PEI) is also an accepted therapy.

Purpose of the Study:

  • To review the efficacy and applications of thermal ablation techniques.
  • To compare RFA outcomes with surgical resection for liver metastases.
  • To explore emerging applications of ablation in other organs.

Main Methods:

  • Review of existing literature and clinical data on thermal ablation.
  • Analysis of survival rates for RFA in hepatocellular carcinoma (HCC) and liver metastases.

Related Experiment Videos

  • Evaluation of morbidity and efficacy in lung and renal ablation.

    • Main Results:

    • RFA and PEI are established treatments for early HCC in Child-Pugh Class A or B cirrhosis.
    • RFA shows promising 5-year survival rates (26-30%) for unresectable liver metastases from colon cancer.
    • Ablation is effective for lung and renal tumors, demonstrating minimal invasiveness and limited morbidity.

    Conclusions:

    • Thermal ablation, particularly RFA, is a viable, minimally invasive treatment option for various cancers.
    • Ablation offers competitive survival outcomes compared to surgery for select patients.
    • Further exploration of ablation for adrenal and pelvic recurrences is warranted.