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Ghrelin improves renal function in mice with ischemic acute renal failure

Ryo Takeda1, Hiroaki Nishimatsu, Etsu Suzuki

  • 1Department of Cardiovascular Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.

Summary

Ghrelin administration improved kidney function and survival in mice with ischemia/reperfusion injury. This protective effect is linked to enhanced endothelial function and insulin-like growth factor-1 (IGF-1) signaling.

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