Stimulation of cell component of the immune response activates exploratory behavior in senescence accelerated OXYS
E V Markova1, V A Kozlov, N A Trofimova
1Institute of Clinical Immunology, Siberian Division of Russian Academy of Medical Sciences, Novosibirsk. evgeniya_markova@mail.ru
Bulletin of Experimental Biology and Medicine
|November 25, 2005
Abstract:
Suppression of the cell component of the immune system and open-field behavior developing in OXYS rats by the age of 3 months are regarded as manifestations of accelerated aging. Stimulation of cell-mediated immune response with BCG vaccine caused a dose-dependent increase of orientation and exploratory activity of OXYS rats in the open field test to virtually the same level as in Wistar rats.
