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Cellular structure and function in normal and neoplastic lymphoid cells.

D Zucker-Franklin

    Archives of Internal Medicine
    |January 1, 1975
    PubMed
    Summary
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    Cellular ultrastructure, including lymphocytes and plasma cells, indicates function in both normal and pathologic states. Identifying structural abnormalities can offer clinical insights despite unknown origins.

    Area of Science:

    • Cellular Biology
    • Pathology
    • Immunology

    Background:

    • The ultrastructure of lymphocytes and plasma cells correlates with their functional status.
    • Pathologic conditions often manifest as specific ultrastructural derangements in these cells.

    Purpose of the Study:

    • To explore the relationship between cellular ultrastructure and function in lymphocytes and plasma cells.
    • To highlight the potential clinical utility of identifying ultrastructural abnormalities.

    Main Methods:

    • Electron microscopy was used to examine the ultrastructure of lymphocytes and plasma cells.
    • Comparative analysis of ultrastructural features in normal versus pathologic cells was performed.

    Main Results:

    Related Experiment Videos

  • Normal cell ultrastructure accurately reflects cellular function.
  • Pathologic conditions exhibit distinct ultrastructural abnormalities linked to functional derangements.
  • Certain structural abnormalities show potential clinical relevance.

    • Conclusions:

    • Cellular ultrastructure serves as a reliable indicator of cell function.
    • Ultrastructural analysis can aid in diagnosing and understanding pathologic conditions.
    • Further research is needed to elucidate the origin and composition of observed abnormalities.