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Updated: Aug 14, 2026

Developing a Rat Model for Bipolar Disorder
Published on: May 2, 2025
Childhood bipolar disorder: a clinical vignette
Robert G Zylstra1, Gina M Defranco, Julia B McKay
1Department of Family Medicine, University of Tennessee College of Medicine, Chattanooga Unit, Chattanooga, TN, USA. robert.zylstra@erlanger.org
Abstract:
Bipolar disorder in children and adolescents can easily be misdiagnosed, as symptom patterns overlap with other mood disorders and attention-deficit/hyperactivity disorder and commonly differ from adult presentations. A detailed description of the child's behavioral history and previous treatment response is critical to accurate diagnosis. Although studies with children are limited, a number of psychopharmaceuticals have been shown to provide therapeutic benefit. Parent/caregiver and educational support are essential components of successful treatment. This article describes an 11-year-old patient with bipolar disorder and then summarizes related treatment issues and options.
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