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APOA1 polymorphisms are associated with variations in serum triglyceride concentrations in hypercholesterolemic

Simone C Sorkin1, Francisco J Forestiero, Mario H Hirata

  • 1Department of Clinical and Toxicological Analysis, School of Pharmaceutical Sciences, University of Sao Paulo, Sao Paulo, Brazil.

Clinical Chemistry and Laboratory Medicine
|November 29, 2005
PubMed
Summary

Apolipoprotein A-I (APOA1) gene variants influence triglyceride levels and response to atorvastatin, particularly in hypercholesterolemic men and women. These APOA1 polymorphisms impact baseline lipid concentrations and treatment outcomes.

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